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Liquid Fill-Finish

F2V - Liquid fill-finish platform

F2V is a sterile liquid fill-finish platform perfect for lab-scale and clinical manufacture thanks to its bench top format.

This technology fills syringes, vials, bottles, catridges and custom containers (including diagnostics) in the same machine, with a fast changeover time of less than five minutes.

F2V helps in multiple ways.  Use it to:

  • De-risk filling and finishing processes quickly and cost-effectively, establishing production-representative processes which can be scaled up without the need to re-validate.
  • Build customer confidence by demonstrating manufacturing know-how.  Show that you understand how to manufacture your device.
  • Stay agile, adapting to late-stage changes in device design, life-cycle volume requirements and market demand. 
  • Integrate with a wide variety of different pump brands and technologies;  Compatible with rotary piston and peristaltic pump

A wide choice of nozzle types and sizes is available to suit the dose volume, liquid and container type. Programmable bottom-up filling enables fine adjustment of needle position, speed of lift and fill rate, avoiding splashing, frothing or contamination of the stoppering zone. A nitrogen purge option is available which uses the same programmable controls as for liquid filling.  Vacuum stoppering is provided for syringes, cartridges and custom containers, or alternatively a 'pick-and-place' module can be selected for stopper insertion and cap application for vials and bottles.

The F2V platform is designed to enable fast, easy scale-up through simple change parts and, if necessary, adding additional pumps to the system. 

Benefits summary: 

  • Liquid fill, nitrogen purge and vacuum stopper on the same machine
  • Fills syringes, vials, cartridges and custom containers
  • Scalable technology
  • Aseptic design
  • Ideal for custom applications
  • Versatile and future proof
  • Recipe management
  • Easy to use, touch-screen display
  • cGMP compliant
  • Integrates with lab balance or high-speed weigh cell


                                                      TECHNICAL DETAILS
Output Up to 180 per hour
Dose range Dependent on pump selection:
Rotary Piston Pump: 0.03-175 mL
Accuracy: Up to +/- 0.1%
Dose Accuracy ±0.1%*
* Dependent upon dose size and liquid properties
Liquid types Aqueous and solvent-based solutions, suspensions
High-viscosity liquids, gels, creams, syrups
Typical container types Pre-Filled Syringes, vials, cartridges, special containers, diagnostic blisters, capsules
Changeover time <5 minutes
Pump options Rotary piston pump
Peristaltic pump
Standard platform content 1 x Fill-Finish base platform
2 x configurable, servo-controlled lift-lower modules
1 x configurable, servo-controlled transfer shuttle
1 x touch-screen control panel (HMI)
1 x electrical control panel
Module configuration options Bottom-up liquid filling
Bottom-up liquid filling with nitrogen purge
Vacuum stoppering
Stopper pick-and-place
Power Supply 230V AC @ 50Hz 13Amp
Weight Approx 60kgs (excluding control panel and touch-screen)
Containment options Active/Passive RABS
Full Isolator
Optional extras Weighing, Ionisation system, nitrogen purge, bulk liquid management (temperature, stirring)


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