'Fail Fast' Approach
A full ergonomic mock- up was key to optimising the system design, revealed that the original configuration overloaded the working chamber. This led to key improvements including an additional chamber, enhanced operator workflow and accessibility, and support for continuous processing - eliminating batch size limitations. Identifying layout constraints early also allowed for necessary facility modifications ahead of installation. Overall, this “fail fast” approach prevented costly issues later in the project and significantly improved the final design. Importantly, the collaboration between Eramol, 3P innovation and IWT resulted in:
- Strong technical knowledge exchange.
- Clear alignment on system design and regulatory expectations.
- Structured project delivery despite differing organisational styles.
Impact
The new aseptic processing capability delivers significant advantages for both Eramol and its customers. For Eramol, it marks a successful transition toward a fully integrated service offering, strengthening its position as a flexible clinical manufacturing partner while increasing control over quality, timelines and delivery.
For customers, it provides access to small-batch, high-value manufacturing with reduced product waste compared to large-scale CDMOs, alongside faster turnaround times and greater flexibility for early-stage clinical trials. Overall, the solution opens up a previously underserved segment of the market.
Client testimonial
"This turnkey solution, led by 3P innovation in collaboration with IWT, demonstrated the strength of a highly integrated, three-way partnership. Each organisation brought complementary expertise across engineering, compliance, and process development, resulting in a cohesive and well-executed solution. From initial concept through to implementation, the team maintained a strong focus on delivering a flexible and robust system aligned with Eramol’s operational needs. The solution achieved minimal line losses for liquid fill products while enabling increased flexibility in presentation formats for sterile liquid products. This is particularly valuable in supporting early-stage IMP manufacturing, where adaptability and efficiency are critical. Importantly, the system was designed and delivered in full alignment with the latest EU GMP Annex 1 requirements, ensuring both compliance and future readiness. The collaborative approach, technical capability, and commitment to quality shown by 3P innovation and IWT were instrumental in the project’s success, and we would confidently recommend them as partners for complex aseptic processing solutions. "
David Cox, Eramol.
